Lineup Field

Cardinals at 49ers: Starting Lineups, Week 3

Final: Cardinals 30, 49ers 36

Cardinals quarterback Jacoby Brissett against 49ers quarterback Brock Purdy. Lineups as listed before kickoff (Cardinals: Sep 27, 2026, 8:56 AM ET; 49ers: Sep 27, 2026, 8:56 AM ET).

Cardinals depth chart · 49ers depth chart · All Week 3 games

Cardinals offense vs 49ers defense

Arizona Cardinals offense against the San Francisco 49ers defense49ers defense: LDE Keion White, LDT Osa Odighizuwa, RDT Gracen Halton, RDE Nick Bosa, WLB Dre Greenlaw, MLB Fred Warner, SLB Luke Gifford, LCB Renardo Green, SS Marques Sigle, FS Ji'Ayir Brown, RCB Deommodore Lenoir. Cardinals offense: WR Michael Wilson, WR Marvin Harrison Jr., LT Paris Johnson Jr., LG Isaac Seumalo, C Hjalte Froholdt, RG Isaiah Adams, RT Elijah Wilkinson, WR Kendrick Bourne, QB Jacoby Brissett, TE Trey McBride, RB Jeremiyah Love49ers defenseCardinals offense#56LDEWhite2 · Kareem#92LDTOdighizuwa2 · Jones#93RDTHalton2 · Thompson Jr.#97RDEBosa2 · HeightOUT#57WLBGreenlaw2 · Wallow#54MLBWarner2 · Bethune#51SLBGifford2 · Dugger#0LCBGreen2 · Jones#36SSSigle2 · Mustapha#27FSBrown2 · Neal#2RCBLenoir2 · Prysock#14WRWilson2 · Brooks#18WRHarrison Jr.2 · Fehoko#70LTJohnson Jr.2 · Fryar#73LGSeumalo2 · Conner#72CFroholdt2 · Gaines II#74RGAdams2 · Gaines II#65RTWilkinson2 · Williams#17WRBourne2 · Duvernay#7QBBrissett2 · Minshew II#85TEMcBride2 · Higgins#4RBLove2 · Allgeier

Cardinals offense

  1. WR#14 Michael WilsonNext up: Jalen Brooks
  2. WR#18 Marvin Harrison Jr.Next up: Simi Fehoko
  3. LT#70 Paris Johnson Jr.Next up: Josh Fryar
  4. LG#73 Isaac SeumaloNext up: Hayden Conner
  5. C#72 Hjalte FroholdtNext up: Jon Gaines II
  6. RG#74 Isaiah AdamsNext up: Jon Gaines II
  7. RT#65 Elijah WilkinsonNext up: Jayden Williams
  8. WR#17 Kendrick BourneNext up: Devin Duvernay
  9. QB#7 Jacoby BrissettNext up: Gardner Minshew II
  10. TE#85 Trey McBrideNext up: Elijah Higgins
  11. RB#4 Jeremiyah LoveNext up: Tyler Allgeier

49ers defense

  1. LDE#56 Keion WhiteNext up: Khalid Kareem
  2. LDT#92 Osa OdighizuwaNext up: Naquan Jones
  3. RDT#93 Gracen HaltonNext up: James Thompson Jr.
  4. RDE#97 Nick Bosa Out (knee)Next up: Romello Height
  5. WLB#57 Dre GreenlawNext up: Garret Wallow
  6. MLB#54 Fred WarnerNext up: Tatum Bethune
  7. SLB#51 Luke GiffordNext up: Jaden Dugger
  8. LCB#0 Renardo GreenNext up: Jack Jones
  9. SS#36 Marques SigleNext up: Malik Mustapha
  10. FS#27 Ji'Ayir BrownNext up: Siran Neal
  11. RCB#2 Deommodore LenoirNext up: Ephesians Prysock

49ers offense vs Cardinals defense

San Francisco 49ers offense against the Arizona Cardinals defenseCardinals defense: LDE Josh Sweat, LDT Roy Lopez, RDT Walter Nolen III, RDE Dante Stills, WLB Jack Gibbens, MLB Mack Wilson Sr., SLB Zaven Collins, LCB Garrett Williams, SS Budda Baker, FS Andrew Wingard, RCB Denzel Burke. 49ers offense: WR Mike Evans, WR Deebo Samuel, LT Trent Williams, LG Connor Colby, C Jake Brendel, RG Dominick Puni, RT Colton McKivitz, WR Jacob Cowing, QB Brock Purdy, TE George Kittle, RB Christian McCaffreyCardinals defense49ers offense#10LDESweat2 · Burch#51LDTLopez2 · BillingsQ#97RDTNolen III2 · Collier#55RDEStills2 · Robinson#50WLBGibbens2 · Sharar#1MLBWilson Sr.2 · Simon#25SLBCollins2 · Browning#21LCBWilliams2 · Thomas V#3SSBaker2 · Taylor-Demerson#28FSWingard2 · Williams Jr.#29RCBBurke2 · Clark#5WREvans2 · WatkinsQ#19WRSamuel2 · Hodge#71LTWilliams2 · Lowe#75LGColby2 · Willis#64CBrendel2 · Patterson#77RGPunino backup listed#68RTMcKivitzno backup listed#4WRCowing2 · Kirk#13QBPurdy2 · Jones#85TEKittle2 · Farrell#23RBMcCaffrey2 · Black

49ers offense

  1. WR#5 Mike Evans Questionable (hip)Next up: Jordan Watkins
  2. WR#19 Deebo SamuelNext up: KhaDarel Hodge
  3. LT#71 Trent WilliamsNext up: Vederian Lowe
  4. LG#75 Connor ColbyNext up: Carver Willis
  5. C#64 Jake BrendelNext up: Jarrett Patterson
  6. RG#77 Dominick PuniNo backup listed
  7. RT#68 Colton McKivitzNo backup listed
  8. WR#4 Jacob CowingNext up: Christian Kirk
  9. QB#13 Brock PurdyNext up: Mac Jones
  10. TE#85 George KittleNext up: Luke Farrell
  11. RB#23 Christian McCaffreyNext up: Kaelon Black

Cardinals defense

  1. LDE#10 Josh SweatNext up: Jordan Burch
  2. LDT#51 Roy Lopez Questionable (groin)Next up: Andrew Billings
  3. RDT#97 Walter Nolen IIINext up: L.J. Collier
  4. RDE#55 Dante StillsNext up: Darius Robinson
  5. WLB#50 Jack GibbensNext up: Karson Sharar
  6. MLB#1 Mack Wilson Sr.Next up: Cody Simon
  7. SLB#25 Zaven CollinsNext up: Baron Browning
  8. LCB#21 Garrett WilliamsNext up: Starling Thomas V
  9. SS#3 Budda BakerNext up: Dadrion Taylor-Demerson
  10. FS#28 Andrew WingardNext up: Wydett Williams Jr.
  11. RCB#29 Denzel BurkeNext up: Kei'Trel Clark

Injury report, Week 3

Cardinals

  • SS Dadrion Taylor-Demerson Out (back)
  • LDT Roy Lopez Questionable (groin)
  • NB Max Melton Questionable (toe)

49ers

  • WR Demarcus Robinson Out (ankle)
  • RDE Nick Bosa Out (knee)
  • RDE Romello Height Out (hand)
  • WR Mike Evans Questionable (hip)

Special teams

Cardinals

  1. PK#38 Chad RylandNo backup listed
  2. P#12 Blake GillikinNo backup listed
  3. H#12 Blake GillikinNo backup listed
  4. PR#81 Devin DuvernayNext up: Michael Wilson
  5. KR#81 Devin DuvernayNext up: Max Melton
  6. LS#59 Casey KreiterNo backup listed

49ers

  1. PK#18 Eddy PineiroNo backup listed
  2. P#15 Corliss WaitmanNo backup listed
  3. H#15 Corliss WaitmanNo backup listed
  4. PR#4 Jacob CowingNext up: Jordan Watkins
  5. KR#19 Deebo SamuelNext up: Jacob Cowing
  6. LS#46 Jon WeeksNo backup listed