Lineup Field

49ers at Rams: Starting Lineups, Week 1

Final: 49ers 27, Rams 7

49ers quarterback Brock Purdy against Rams quarterback Matthew Stafford. Lineups as listed before kickoff (49ers: Sep 10, 2026, 8:01 AM ET; Rams: Sep 10, 2026, 8:01 AM ET).

49ers depth chart · Rams depth chart · All Week 1 games

49ers offense vs Rams defense

San Francisco 49ers offense against the Los Angeles Rams defenseRams defense: LDE Kobie Turner, NT Poona Ford, RDE Aaron Donald, WLB Byron Young, LILB Nate Landman, RILB Omar Speights, SLB Myles Garrett, LCB Jaylen Watson, SS Kamren Kinchens, FS Kam Curl, RCB Trent McDuffie. 49ers offense: WR Mike Evans, WR Deebo Samuel, LT Trent Williams, LG Connor Colby, C Jake Brendel, RG Dominick Puni, RT Colton McKivitz, WR De'Zhaun Stribling, QB Brock Purdy, TE George Kittle, RB Christian McCaffreyRams defense49ers offense#91LDETurner2 · Davis#97NTFord2 · Hamilton#99RDEDonald2 · FiskeOUT#0WLBYoung2 · Stewart#53LILBLandman2 · Stuard#48RILBSpeights2 · Dolac#95SLBGarrett2 · Johnson#35LCBWatsonno backup listed#5SSKinchens2 · McCollough#3FSCurlno backup listed#22RCBMcDuffie2 · Forbes Jr.#5WREvans2 · Robinson#19WRSamuel2 · Watkins#71LTWilliams2 · Lowe#75LGColby2 · Willis#64CBrendel2 · Patterson#77RGPunino backup listed#68RTMcKivitzno backup listed#7WRStribling2 · Cowing#13QBPurdy2 · Jones#85TEKittle2 · Tonges#23RBMcCaffrey2 · Black

49ers offense

  1. WR#5 Mike EvansNext up: Demarcus Robinson
  2. WR#19 Deebo SamuelNext up: Jordan Watkins
  3. LT#71 Trent WilliamsNext up: Vederian Lowe
  4. LG#75 Connor ColbyNext up: Carver Willis
  5. C#64 Jake BrendelNext up: Jarrett Patterson
  6. RG#77 Dominick PuniNo backup listed
  7. RT#68 Colton McKivitzNo backup listed
  8. WR#7 De'Zhaun StriblingNext up: Jacob Cowing
  9. QB#13 Brock PurdyNext up: Mac Jones
  10. TE#85 George KittleNext up: Jake Tonges
  11. RB#23 Christian McCaffreyNext up: Kaelon Black

Rams defense

  1. LDE#91 Kobie TurnerNext up: Tyler Davis
  2. NT#97 Poona FordNext up: Ty Hamilton
  3. RDE#99 Aaron Donald Out (not injury related - resting player)Next up: Braden Fiske
  4. WLB#0 Byron YoungNext up: Josaiah Stewart
  5. LILB#53 Nate LandmanNext up: Grant Stuard
  6. RILB#48 Omar SpeightsNext up: Shaun Dolac
  7. SLB#95 Myles GarrettNext up: Desjuan Johnson
  8. LCB#35 Jaylen WatsonNo backup listed
  9. SS#5 Kamren KinchensNext up: Jaylen McCollough
  10. FS#3 Kam CurlNo backup listed
  11. RCB#22 Trent McDuffieNext up: Emmanuel Forbes Jr.

Rams offense vs 49ers defense

Los Angeles Rams offense against the San Francisco 49ers defense49ers defense: LDE Keion White, LDT Osa Odighizuwa, RDT Gracen Halton, RDE Nick Bosa, WLB Dre Greenlaw, MLB Fred Warner, SLB Luke Gifford, LCB Renardo Green, SS Malik Mustapha, FS Ji'Ayir Brown, RCB Deommodore Lenoir. Rams offense: WR Puka Nacua, WR Davante Adams, LT Alaric Jackson, LG Steve Avila, C Coleman Shelton, RG Kevin Dotson, RT Warren McClendon Jr., WR Jordan Whittington, QB Matthew Stafford, TE Colby Parkinson, RB Kyren Williams49ers defenseRams offense#56LDEWhite2 · Kareem#92LDTOdighizuwa2 · West#93RDTHalton2 · Thompson Jr.#97RDEBosa2 · Height#57WLBGreenlaw2 · Wallow#54MLBWarner2 · Bethune#51SLBGifford2 · Dugger#0LCBGreen2 · Jones#6SSMustapha2 · Sigle#27FSBrown2 · Neal#2RCBLenoir2 · Prysock#12WRNacua2 · Mumpfield#17WRAdams2 · Atwell#77LTJackson2 · Quessenberry#73LGAvila2 · Limmer#65CShelton2 · McMahon#69RGDotson2 · Dedich#71RTMcClendon Jr.2 · Trost#88WRWhittington2 · Smith#9QBStafford2 · Bennett IV#84TEParkinson2 · Higbee#23RBWilliams2 · Corum

Rams offense

  1. WR#12 Puka NacuaNext up: Konata Mumpfield
  2. WR#17 Davante AdamsNext up: Tutu Atwell
  3. LT#77 Alaric JacksonNext up: David Quessenberry
  4. LG#73 Steve AvilaNext up: Beaux Limmer
  5. C#65 Coleman SheltonNext up: Dylan McMahon
  6. RG#69 Kevin DotsonNext up: Justin Dedich
  7. RT#71 Warren McClendon Jr.Next up: Keagen Trost
  8. WR#88 Jordan WhittingtonNext up: Xavier Smith
  9. QB#9 Matthew StaffordNext up: Stetson Bennett IV
  10. TE#84 Colby ParkinsonNext up: Tyler Higbee
  11. RB#23 Kyren WilliamsNext up: Blake Corum

49ers defense

  1. LDE#56 Keion WhiteNext up: Khalid Kareem
  2. LDT#92 Osa OdighizuwaNext up: C.J. West
  3. RDT#93 Gracen HaltonNext up: James Thompson Jr.
  4. RDE#97 Nick BosaNext up: Romello Height
  5. WLB#57 Dre GreenlawNext up: Garret Wallow
  6. MLB#54 Fred WarnerNext up: Tatum Bethune
  7. SLB#51 Luke GiffordNext up: Jaden Dugger
  8. LCB#0 Renardo GreenNext up: Jack Jones
  9. SS#6 Malik MustaphaNext up: Marques Sigle
  10. FS#27 Ji'Ayir BrownNext up: Siran Neal
  11. RCB#2 Deommodore LenoirNext up: Ephesians Prysock

Injury report, Week 1

49ers

  • RDT Alfred Collins Out (knee)

Rams

  • RDE Aaron Donald Out (not injury related - resting player)

Special teams

49ers

  1. PK#18 Eddy PineiroNo backup listed
  2. P#15 Corliss WaitmanNo backup listed
  3. H#15 Corliss WaitmanNo backup listed
  4. PR#4 Jacob CowingNext up: Jordan Watkins
  5. KR#19 Deebo SamuelNext up: Jacob Cowing
  6. LS#46 Jon WeeksNo backup listed

Rams

  1. PK#92 Harrison MevisNo backup listed
  2. P#42 Ethan EvansNo backup listed
  3. H#42 Ethan EvansNo backup listed
  4. PR#19 Xavier SmithNext up: Kyren Williams
  5. KR#88 Jordan WhittingtonNext up: Ronnie Rivers
  6. LS#49 Joe CardonaNo backup listed